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1.

Trial of Solanezumab in Preclinical Alzheimer's Disease.

Sperling, Reisa A; Donohue, Michael C; Raman, Rema; Rafii, Michael S; Johnson, Keith; Masters, Colin L; van Dyck, Christopher H; Iwatsubo, Takeshi; Marshall, Gad A; Yaari, Roy; Mancini, Michele; Holdridge, Karen C; Case, Michael; Sims, John R; Aisen, Paul S.

N Engl J Med; 389(12): 1096-1107, 2023 Sep 21.

Artículo en Inglés | MEDLINE | ID: mdl-37458272

2.

Safety and tolerability of intravenous immunoglobulin infusion in Down syndrome regression disorder.

Santoro, Jonathan D; Jafarpour, Saba; Khoshnood, Mellad M; Boyd, Natalie K; Vogel, Benjamin N; Nguyen, Lina; Saucier, Laura E; Partridge, Rebecca; Tiongson, Emmanuelle; Ramos-Platt, Leigh; Nagesh, Deepti; Ho, Eugenia; Rosser, Tena; Ahsan, Nusrat; Mitchell, Wendy G; Rafii, Michael S.

Am J Med Genet A; 194(5): e63524, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38169137

3.

Plasma Aß42/Aß40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.

Rissman, Robert A; Langford, Oliver; Raman, Rema; Donohue, Michael C; Abdel-Latif, Sara; Meyer, Matthew R; Wente-Roth, Traci; Kirmess, Kristopher M; Ngolab, Jennifer; Winston, Charisse N; Jimenez-Maggiora, Gustavo; Rafii, Michael S; Sachdev, Pallavi; West, Tim; Yarasheski, Kevin E; Braunstein, Joel B; Irizarry, Michael; Johnson, Keith A; Aisen, Paul S; Sperling, Reisa A.

Alzheimers Dement; 20(2): 1214-1224, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-37932961

4.

Adverse childhood experiences and the development of Down syndrome regression disorder.

Wang, Sarah; Patel, Lina; Sannar, Elise A; Khoshnood, Mellad; Boyd, Natalie K; Mendez, Lorena; Spinazzi, Noemi A; Quinn, Eileen A; Rafii, Michael S; Santoro, Jonathan D.

Am J Med Genet A; 191(7): 1769-1782, 2023 07.

Artículo en Inglés | MEDLINE | ID: mdl-37017126

5.

The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer's disease.

Rafii, Michael S; Sperling, Reisa A; Donohue, Michael C; Zhou, Jin; Roberts, Claire; Irizarry, Michael C; Dhadda, Shobha; Sethuraman, Gopalan; Kramer, Lynn D; Swanson, Chad J; Li, David; Krause, Stephen; Rissman, Robert A; Walter, Sarah; Raman, Rema; Johnson, Keith A; Aisen, Paul S.

Alzheimers Dement; 19(4): 1227-1233, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-35971310

6.

Addressing challenges in health care and research for people with Down syndrome.

Fortea, Juan; McGlinchey, Eimear; Espinosa, Joaquín M; Rafii, Michael S.

Lancet; 403(10439): 1830-1833, 2024 May 11.

Artículo en Inglés | MEDLINE | ID: mdl-38521088

7.

Initiation of symptomatic medication in Alzheimer's disease clinical trials: Hypothetical versus treatment policy approach.

Donohue, Michael C; Model, Fabian; Delmar, Paul; Volye, Nicola; Liu-Seifert, Hong; Rafii, Michael S; Aisen, Paul S.

Alzheimers Dement; 16(5): 797-803, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-32270600

8.

Further understanding the connection between Alzheimer's disease and Down syndrome.

Snyder, Heather M; Bain, Lisa J; Brickman, Adam M; Carrillo, Maria C; Esbensen, Anna J; Espinosa, Joaquin M; Fernandez, Fabian; Fortea, Juan; Hartley, Sigan L; Head, Elizabeth; Hendrix, James; Kishnani, Priya S; Lai, Florence; Lao, Patrick; Lemere, Cynthia; Mobley, William; Mufson, Elliott J; Potter, Huntington; Zaman, Shahid H; Granholm, Ann-Charlotte; Rosas, H Diana; Strydom, Andre; Whitten, Michelle Sie; Rafii, Michael S.

Alzheimers Dement; 16(7): 1065-1077, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32544310

9.

Estimating the Evolution of Disease in the Parkinson's Progression Markers Initiative.

Iddi, Samuel; Li, Dan; Aisen, Paul S; Rafii, Michael S; Litvan, Irene; Thompson, Wesley K; Donohue, Michael C.

Neurodegener Dis; 18(4): 173-190, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-30089306

10.

Down Syndrome in a New Era for Alzheimer Disease.

Rafii, Michael S; Fortea, Juan.

JAMA; 330(22): 2157-2158, 2023 12 12.

Artículo en Inglés | MEDLINE | ID: mdl-37991807

11.

Cerebral amyloid angiopathy in Down syndrome and sporadic and autosomal-dominant Alzheimer's disease.

Carmona-Iragui, María; Balasa, Mircea; Benejam, Bessy; Alcolea, Daniel; Fernández, Susana; Videla, Laura; Sala, Isabel; Sánchez-Saudinós, María Belén; Morenas-Rodriguez, Estrella; Ribosa-Nogué, Roser; Illán-Gala, Ignacio; Gonzalez-Ortiz, Sofía; Clarimón, Jordi; Schmitt, Frederick; Powell, David K; Bosch, Beatriz; Lladó, Albert; Rafii, Michael S; Head, Elizabeth; Molinuevo, José Luis; Blesa, Rafael; Videla, Sebastián; Lleó, Alberto; Sánchez-Valle, Raquel; Fortea, Juan.

Alzheimers Dement; 13(11): 1251-1260, 2017 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-28463681

12.

Advances in Alzheimer's disease drug development.

Rafii, Michael S; Aisen, Paul S.

BMC Med; 13: 62, 2015 Mar 25.

Artículo en Inglés | MEDLINE | ID: mdl-25857341

13.

A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease.

Rafii, Michael S; Baumann, Tiffany L; Bakay, Roy A E; Ostrove, Jeffrey M; Siffert, Joao; Fleisher, Adam S; Herzog, Christopher D; Barba, David; Pay, Mary; Salmon, David P; Chu, Yaping; Kordower, Jeffrey H; Bishop, Kathie; Keator, David; Potkin, Steven; Bartus, Raymond T.

Alzheimers Dement; 10(5): 571-81, 2014 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-24411134

14.

From understanding to action: Exploring molecular connections of Down syndrome to Alzheimer's disease for targeted therapeutic approach.

Sukreet, Sonal; Rafii, Michael S; Rissman, Robert A.

Alzheimers Dement (Amst); 16(2): e12580, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38623383

15.

Neuroimaging abnormalities associated with immunotherapy responsiveness in Down syndrome regression disorder.

Santoro, Jonathan D; Khoshnood, Mellad M; Jafarpour, Saba; Nguyen, Lina; Boyd, Natalie K; Vogel, Benjamin N; Kammeyer, Ryan; Patel, Lina; Manning, Melanie A; Rachubinski, Angela L; Filipink, Robyn A; Baumer, Nicole T; Santoro, Stephanie L; Franklin, Catherine; Tamrazi, Benita; Yeom, Kristen W; Worley, Gordon; Espinosa, Joaquin M; Rafii, Michael S.

Ann Clin Transl Neurol; 11(4): 1034-1045, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38375538

16.

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study.

Wisch, Julie K; McKay, Nicole S; Boerwinkle, Anna H; Kennedy, James; Flores, Shaney; Handen, Benjamin L; Christian, Bradley T; Head, Elizabeth; Mapstone, Mark; Rafii, Michael S; O'Bryant, Sid E; Price, Julie C; Laymon, Charles M; Krinsky-McHale, Sharon J; Lai, Florence; Rosas, H Diana; Hartley, Sigan L; Zaman, Shahid; Lott, Ira T; Tudorascu, Dana; Zammit, Matthew; Brickman, Adam M; Lee, Joseph H; Bird, Thomas D; Cohen, Annie; Chrem, Patricio; Daniels, Alisha; Chhatwal, Jasmeer P; Cruchaga, Carlos; Ibanez, Laura; Jucker, Mathias; Karch, Celeste M; Day, Gregory S; Lee, Jae-Hong; Levin, Johannes; Llibre-Guerra, Jorge; Li, Yan; Lopera, Francisco; Roh, Jee Hoon; Ringman, John M; Supnet-Bell, Charlene; van Dyck, Christopher H; Xiong, Chengjie; Wang, Guoqiao; Morris, John C; McDade, Eric; Bateman, Randall J; Benzinger, Tammie L S; Gordon, Brian A; Ances, Beau M.

Lancet Neurol; 23(5): 500-510, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38631766

17.

Functional brain imaging in the clinical assessment of consciousness.

Rafii, Michael S; Brewer, James B.

PLoS Biol; 8(11): e1000548, 2010 Nov 30.

Artículo en Inglés | MEDLINE | ID: mdl-21151340

18.

Detection and treatment of Alzheimer's disease in its preclinical stage.

Rafii, Michael S; Aisen, Paul S.

Nat Aging; 3(5): 520-531, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-37202518

19.

Amyloid-Lowering Monoclonal Antibodies for the Treatment of Early Alzheimer's Disease.

Leisher, Solana; Bohorquez, Adriana; Gay, Marcus; Garcia, Victoria; Jones, Renarda; Baldaranov, Dobri; Rafii, Michael S.

CNS Drugs; 37(8): 671-677, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37470978

20.

Safety and tolerability of lumbar puncture for the evaluation of Alzheimer's disease.

Baldaranov, Dobri; Garcia, Victoria; Miller, Garrett; Donohue, Michael C; Shaw, Leslie M; Weiner, Mike; Petersen, Ronald C; Aisen, Paul; Raman, Rema; Rafii, Michael S.

Alzheimers Dement (Amst); 15(2): e12431, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37091309

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